Malaria risk in Ethiopian cities and countryside
Official title: Malaria Epidemiology across Rural and Urban Landscapes in Ethiopia
Funded at University of California-Irvine · NIH-11515813 · Data updated 2026-11-12
This work looks at how malaria spreads and whether mosquito control can better protect people living in Ethiopian cities and rural areas where the invasive Anopheles stephensi mosquito is present.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California-Irvine NIH-funded |
| Lab location | 1 site (Irvine, United States) |
| Project start | April 15, 2017 |
| Project end | March 31, 2029 |
| Funding year | 2026 |
| Award (this year) | $43,200 |
| NIH project number | 3U19AI129326-10S2 |
| Project ID | NIH-11515813 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal participants are residents of selected urban and nearby rural areas in Ethiopia, especially in neighborhoods where Anopheles stephensi is suspected or confirmed, who are willing to provide health information and brief blood samples.
✕Less likely to help
People who live outside the study sites or outside Ethiopia, or those not willing to provide samples or health information, are unlikely to receive direct benefit from participation.
What this research studies
If you live in Ethiopia, researchers will compare malaria risk from cities to the countryside by tracking cases, testing blood for infection and antibodies, and mapping where malaria-carrying mosquitoes are found. Teams will collect and identify mosquitoes, paying special attention to the invasive Anopheles stephensi, and test them for malaria parasites. The project will also compare communities with different mosquito-control programs to see which approaches are linked to fewer infections. Findings will be used to recommend cost-effective, locally tailored control strategies for urban and rural settings.
Why it matters
Potential benefit: If successful, this work could guide targeted mosquito-control strategies that reduce malaria cases in urban and rural Ethiopian communities.
How similar studies have gone: Past programs have achieved large reductions in rural malaria in parts of sub‑Saharan Africa, but efforts focused on urban malaria and controlling the Anopheles stephensi invasion are newer and the best strategies are still being worked out.
Where this research is happening
-
University of California-Irvine
Irvine, United States Active
Researchers
- Principal investigator: Yan, Guiyun — University of California-Irvine
- Study coordinator: Yan, Guiyun
Related research
Other NIH-funded projects on the same topics.
-
Digital malaria surveillance in Ethiopia to improve outbreak detection
A collaboration to add a malaria-specific digital module to an existing surveillance system in Africa to help detect and respond to outbreaks faster.
-
Cross-sector partnership uses digital malaria surveillance in Ethiopia
A US-based team will adapt and test a digital malaria surveillance module in SORMAS to help detect and respond to malaria outbreaks in Ethiopia.
-
Malaria control project in Western Kenya to reduce illness and deaths
A large, multi-year effort in western Kenya will help track malaria spread and test ways to prevent transmission so fewer people get sick or die.
-
Optimizing tafenoquine dose to prevent relapse of vivax malaria in Asia
A study tests the best tafenoquine dose to prevent P. vivax malaria relapse in people in East Asia and Oceania.
-
Optimizing tafenoquine dose to prevent P. vivax malaria relapses in Asia
A study to find the best single-dose tafenoquine amount to prevent relapse of P. vivax malaria in people in East Asia and Oceania.
-
Severe malaria and brain risk in children
This grant studies how severe malaria in young children can affect brain development and long-term thinking and behavior, with a focus on kids in Uganda.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.