Making sepsis care more consistent and equitable
Reducing Variation in Sepsis Outcomes
['FUNDING_R01'] · YALE UNIVERSITY · NIH-11401061
This project uses a coalition-based leadership program to help hospitals and local partners deliver more consistent, better care to people with sepsis.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | YALE UNIVERSITY (nih funded) |
| Locations | 1 site (NEW HAVEN, UNITED STATES) |
| Trial ID | NIH-11401061 on ClinicalTrials.gov |
What this research studies
You would see hospital leaders and community partners working together to improve how sepsis is treated across regions. The team will adapt and deliver a coalition-based leadership intervention in eight U.S. health systems and their surrounding communities to change organizational culture and care processes. They will collect hospital-level and patient outcome data—such as antibiotic use, complications, and readmissions—to track whether differences in sepsis care shrink. The program focuses on reducing gaps for groups who currently have worse sepsis outcomes.
Who could benefit from this research
Good fit: Ideal participants are patients treated for sepsis at the participating health systems, especially those from communities that currently experience worse sepsis outcomes.
Not a fit: Patients treated outside the participating systems or those with very advanced illnesses unlikely to respond to changes in care processes may not see direct benefit.
Why it matters
Potential benefit: If successful, this could make sepsis care more reliable and equitable, reducing complications and readmissions for patients.
How similar studies have performed: Previous work shows coalition-based leadership can improve complex health outcomes, but applying this approach specifically to reduce differences in sepsis care is a new, prospective effort.
Where this research is happening
NEW HAVEN, UNITED STATES
- YALE UNIVERSITY — NEW HAVEN, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: LINNANDER, ERIKA — YALE UNIVERSITY
- Study coordinator: LINNANDER, ERIKA
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.