Making Opioid Use Disorder Treatments Work for More People
Design and analysis advances to improve generalizability of clinical trials for treating opioid use disorder
This project aims to make treatments for opioid use disorder more effective and available for a wider range of people.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Columbia University Health Sciences NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-11116872 on NIH RePORTER |
What this research studies
Many people struggle with opioid use disorder, and while medications can help, it's often hard to stay engaged with treatment long-term. We've noticed that treatments sometimes work better in controlled research settings than in everyday life, which means not everyone benefits equally. This project is working on new ways to design and understand research so that future treatment options are truly helpful for all kinds of people living with opioid use disorder. Our goal is to close the gap between what we learn in studies and what works best for you in the real world.
Who could benefit from this research
Good fit: Patients with opioid use disorder who might participate in future clinical trials could ultimately benefit from the improved design and analysis methods developed here.
Not a fit: Patients seeking immediate direct treatment or participation in a new clinical trial would not directly benefit from this methodological grant.
Why it matters
Potential benefit: If successful, this work could lead to future clinical trials that better reflect and serve the diverse needs of individuals with opioid use disorder, improving treatment outcomes for more people.
How similar studies have performed: This project proposes to develop novel design and analytic approaches to improve trial generalizability, building on existing statistical and epidemiological methods.
Where this research is happening
New York, United States
- Columbia University Health Sciences — New York, United States (Active)
Researchers
- Principal investigator: Rudolph, Kara Elizabeth — Columbia University Health Sciences
- Study coordinator: Rudolph, Kara Elizabeth
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.