Making new fluorinated compounds easier to create for medicine
Official title: Synthetic Methods to Make Emerging Fluorinated Groups More Accessible
Funded at University of California at Davis · NIH-10879121 · Data updated 2026-11-12
This study is working on finding safer and easier ways to create special chemical groups that can help make better medicines, especially for those that have been hard to use in the past.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California at Davis NIH-funded |
| Lab location | 1 site (Davis, United States) |
| Project start | July 1, 2023 |
| Project end | June 30, 2028 |
| Funding year | 2024 |
| Award (this year) | $370,303 |
| NIH project number | 5R35GM150861-02 |
| Project ID | NIH-10879121 on NIH RePORTER |
Who could benefit from this research
✓Could help
Patients who may benefit from this research are those with conditions treated by pharmaceuticals that could be enhanced through the use of novel fluorinated compounds.
✕Less likely to help
Patients who are not affected by conditions requiring fluorinated pharmaceuticals may not receive any benefit from this research.
What this research studies
This research focuses on improving the methods used to synthesize fluorinated groups, which are important components in many pharmaceuticals. Currently, certain fluorinated groups are underutilized in drug development due to the challenges and hazards associated with their synthesis. The project aims to develop safer and more accessible synthetic methods for these compounds, specifically targeting groups like SF5 and N(CF3)2. By addressing these synthetic bottlenecks, the research hopes to enhance the availability of effective medications that incorporate these promising fluorinated groups.
Why it matters
Potential benefit: If successful, this research could lead to the development of new and more effective medications that utilize fluorinated compounds.
How similar studies have gone: Previous research has shown success in improving synthetic methods for other fluorinated groups, indicating potential for this approach.
Where this research is happening
-
University of California at Davis
Davis, United States Active
Researchers
- Principal investigator: Pitts, Cody Ross — University of California at Davis
- Study coordinator: Pitts, Cody Ross
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.