Making Naloxone More Available to Prevent Opioid Overdose

Improving Access to Naloxone to Prevent Opioid Overdose Deaths Within Community-based Programs that Serve People Who Use Drugs

NIH-funded research Research Triangle Institute · NIH-11121958

This project helps community programs give out more naloxone, a life-saving medication, to people who use drugs across California to prevent overdose deaths.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionResearch Triangle Institute NIH-funded
Lab location1 site (Research Triangle Park, United States)
Project IDNIH-11121958 on NIH RePORTER

What this research studies

We are testing a new way to help community programs better distribute naloxone, which can reverse opioid overdoses. This approach, called SAIA-Naloxone, guides programs through steps like screening participants, providing training on how to use naloxone, and ensuring people can get refills. Our goal is to make sure more people who use drugs have access to naloxone when they need it most. We are conducting a large-scale comparison to see how well this method works and if it is cost-effective.

Who could benefit from this research

Good fit: This project is designed to benefit people who use drugs and are served by community-based programs in California, by increasing their access to naloxone.

Not a fit: Patients not served by the participating community-based programs in California may not directly benefit from this specific intervention.

Why it matters

Potential benefit: If successful, this work could significantly reduce opioid overdose deaths by making naloxone more widely available and effectively distributed through community programs.

How similar studies have performed: Pilot work has shown that this approach led to a significant increase in the number of people receiving naloxone and doses distributed per week.

Where this research is happening

Research Triangle Park, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.