Making linked real-world diabetes data more reliable
Improving the VAlidity of LInked real-world DAta sTudiEs for Diabetes Mellitus research (VALIDATE-DM)
['FUNDING_R01'] · HARVARD PILGRIM HEALTH CARE, INC. · NIH-11302635
This project improves how linked health records are used to learn which diabetes medicines work best and are safest for people with diabetes.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | HARVARD PILGRIM HEALTH CARE, INC. (nih funded) |
| Locations | 1 site (Canton, UNITED STATES) |
| Trial ID | NIH-11302635 on ClinicalTrials.gov |
What this research studies
If you have diabetes, this project looks at how doctors and researchers combine different kinds of health records—like electronic health records and insurance claims—to learn which glucose-lowering medicines work best and are safest for people like you. The team links large datasets and develops better study designs and statistical methods to reduce errors and misleading results that can come from incomplete or mismatched records. They focus on comparing different diabetes drugs using these linked records while testing methods to spot and correct biases. The goal is to make real-world evidence more trustworthy so it can better inform treatment choices.
Who could benefit from this research
Good fit: People with type 1 or type 2 diabetes whose medical records and insurance claims can be linked in participating health systems or insurers would be most relevant to this work.
Not a fit: People without diabetes, those whose records are not in the participating databases, or anyone seeking an immediate change in their personal treatment are unlikely to receive direct benefits from this project.
Why it matters
Potential benefit: If successful, this work could give patients clearer, more trustworthy information about the benefits and risks of different diabetes medicines.
How similar studies have performed: Previous studies using claims and EHR data have provided useful insights about diabetes treatments, but linking datasets and correcting for biases remains a developing area with mixed success.
Where this research is happening
Canton, UNITED STATES
- HARVARD PILGRIM HEALTH CARE, INC. — Canton, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: TOH, DARREN — HARVARD PILGRIM HEALTH CARE, INC.
- Study coordinator: TOH, DARREN
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.