Making it easier for people with inherited cancer risk to get the right screenings and follow-up

Closing the GAPS: Guideline Adherence, Prevention and Surveillance in Hereditary Cancer

NIH-funded research Nest Genomics · NIH-11350386

This project builds electronic health record tools to help people with inherited cancer risks get recommended genetic testing, screening, and long-term follow-up.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionNest Genomics NIH-funded
Lab location1 site (Albany, United States)
Project IDNIH-11350386 on NIH RePORTER

What this research studies

If you have a personal or family history suggesting inherited cancer risk, this project will link genetic testing and results into the electronic health record so clinicians and patients can see and act on them. It sets up automated prompts and clinical decision support to remind clinicians about guideline-recommended screenings and prevention steps, and it streamlines consent, test ordering, and result delivery. The team will pilot these processes for hereditary cancer care, including outreach for adolescent and young adult patients, and track whether people receive recommended surveillance over time. The goal is a durable, longitudinal system that keeps people informed and helps clinicians follow best practices.

Who could benefit from this research

Good fit: Ideal candidates are people with a known or suspected inherited cancer syndrome or a strong personal or family history of hereditary cancers, including adolescent and young adult patients.

Not a fit: People without a personal or family history suggesting inherited cancer risk or those who do not receive care at participating health systems may not directly benefit from this project.

Why it matters

Potential benefit: If successful, this could make it easier for people with inherited cancer risk to get timely genetic testing, appropriate screenings, and coordinated follow-up through their medical record.

How similar studies have performed: Prior programs that added genetic results and decision support to electronic records have improved testing and follow-up in some settings, but comprehensive, long-term systems for hereditary cancer management are still emerging.

Where this research is happening

Albany, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Cancer CenterCancer PatientCancers
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.