Making it easier for people with inherited cancer risk to get the right screenings and follow-up
Official title: Closing the GAPS: Guideline Adherence, Prevention and Surveillance in Hereditary Cancer
Funded at Nest Genomics · NIH-11350386 · Data updated 2026-11-12
This project builds electronic health record tools to help people with inherited cancer risks get recommended genetic testing, screening, and long-term follow-up.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Nest Genomics NIH-funded |
| Lab location | 1 site (Albany, United States) |
| Project start | September 19, 2024 |
| Project end | August 31, 2027 |
| Funding year | 2025 |
| Award (this year) | $1,115,854 |
| NIH project number | 4R42HG013908-02 |
| Project ID | NIH-11350386 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates are people with a known or suspected inherited cancer syndrome or a strong personal or family history of hereditary cancers, including adolescent and young adult patients.
✕Less likely to help
People without a personal or family history suggesting inherited cancer risk or those who do not receive care at participating health systems may not directly benefit from this project.
What this research studies
If you have a personal or family history suggesting inherited cancer risk, this project will link genetic testing and results into the electronic health record so clinicians and patients can see and act on them. It sets up automated prompts and clinical decision support to remind clinicians about guideline-recommended screenings and prevention steps, and it streamlines consent, test ordering, and result delivery. The team will pilot these processes for hereditary cancer care, including outreach for adolescent and young adult patients, and track whether people receive recommended surveillance over time. The goal is a durable, longitudinal system that keeps people informed and helps clinicians follow best practices.
Why it matters
Potential benefit: If successful, this could make it easier for people with inherited cancer risk to get timely genetic testing, appropriate screenings, and coordinated follow-up through their medical record.
How similar studies have gone: Prior programs that added genetic results and decision support to electronic records have improved testing and follow-up in some settings, but comprehensive, long-term systems for hereditary cancer management are still emerging.
Where this research is happening
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Nest Genomics
Albany, United States Active
Researchers
- Principal investigator: Snir, Moran — Nest Genomics
- Study coordinator: Snir, Moran
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.