Making HIV prevention and care dollars go farther

Cost-Effectiveness of Preventing HIV Complications

NIH-funded research Massachusetts General Hospital · NIH-11337408

This project uses computer models to compare HIV testing, treatment, and prevention approaches to find what helps people with or at risk for HIV the most.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionMassachusetts General Hospital NIH-funded
Lab location1 site (Boston, United States)
Project IDNIH-11337408 on NIH RePORTER

What this research studies

From my perspective, the team uses a computer microsimulation called CEPAC to simulate how different HIV testing, linkage, treatment, and prevention strategies affect people's health and costs. They will add optimization methods to account for the complexity of multiple payers and funding streams at state and national levels. The researchers will work with the Massachusetts Department of Public Health to tailor analyses to local epidemics while also examining national priorities. The goal is to identify which combinations of programs produce the biggest health gains for the money spent.

Who could benefit from this research

Good fit: People living with HIV and people at risk for HIV—especially those in Massachusetts or served by U.S. public health programs—are the populations whose care and prevention needs are modeled.

Not a fit: Because this is a modeling and policy project rather than a clinical trial, it does not provide direct medical treatment or immediate individual benefits.

Why it matters

Potential benefit: If successful, this work could help health departments and clinics spend HIV prevention and care funds where they will produce more viral suppression and fewer new infections.

How similar studies have performed: Similar decision models, including prior CEPAC work, have been used to inform HIV policy and budgeting, though they guide programs rather than provide direct care.

Where this research is happening

Boston, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Acquired Immune Deficiency Syndrome VirusAcquired Immunodeficiency Syndrome Virus
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.