Making head and neck cancer models better for patients
Improving the translational value of head and neck cancer patient-in-mouse models
['FUNDING_R37'] · UNIVERSITY OF WISCONSIN-MADISON · NIH-11211993
This work helps researchers create more accurate models of head and neck cancer using patient tumor samples, so new treatments can be tested more effectively.
Quick facts
| Phase | ['FUNDING_R37'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF WISCONSIN-MADISON (nih funded) |
| Locations | 1 site (MADISON, UNITED STATES) |
| Trial ID | NIH-11211993 on ClinicalTrials.gov |
What this research studies
We are working to improve how patient-derived tumor models are created and used to better understand head and neck cancer. These models, which involve implanting patient tumor samples into mice, help us learn about tumor biology and test new treatments. Our goal is to understand how initial decisions in handling tumor samples affect the results of these studies. By making these models more reliable, we hope to find better ways to care for people with head and neck cancer.
Who could benefit from this research
Good fit: This research uses tumor samples from head and neck cancer patients, but does not involve direct patient participation in the current experiments.
Not a fit: Patients not diagnosed with head and neck cancer would not directly benefit from this specific research.
Why it matters
Potential benefit: If successful, this work could lead to more accurate testing of new head and neck cancer treatments, potentially improving patient outcomes.
How similar studies have performed: Patient-derived models are commonly used, but this work aims to improve their foundational methods, which is a novel focus.
Where this research is happening
MADISON, UNITED STATES
- UNIVERSITY OF WISCONSIN-MADISON — MADISON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: KIMPLE, RANDALL J. — UNIVERSITY OF WISCONSIN-MADISON
- Study coordinator: KIMPLE, RANDALL J.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.