Making DNA Sequencing More Powerful and Accessible
Realizing the potential of long-read sequencing technology
This project is developing new ways to read DNA more completely and accurately, which will help scientists better understand human biology and disease.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California Santa Cruz NIH-funded |
| Lab location | 1 site (Santa Cruz, United States) |
| Project ID | NIH-11117000 on NIH RePORTER |
What this research studies
This project aims to make DNA sequencing, especially a newer method called long-read sequencing, much better and easier to use. Currently, these advanced methods aren't as developed as older ones, limiting their use in understanding health and disease. Our work will create detailed maps of all the active genes in human and mouse tissues, which is crucial for many medical studies. We also plan to create a new, very accurate sequencing tool that anyone can use, making cutting-edge genetic research more widely available.
Who could benefit from this research
Good fit: This foundational research does not directly involve patient participation, but future studies building on this technology could benefit patients with various genetic conditions.
Not a fit: Patients seeking immediate clinical interventions or direct treatment options would not find direct benefit from this basic science and methods development project.
Why it matters
Potential benefit: If successful, this work could lead to a deeper understanding of human diseases by providing more complete genetic information, potentially speeding up the discovery of new treatments.
How similar studies have performed: While long-read sequencing technology exists, this project focuses on developing novel molecular and computational methods to overcome current limitations and expand its utility.
Where this research is happening
Santa Cruz, United States
- University of California Santa Cruz — Santa Cruz, United States (Active)
Researchers
- Principal investigator: Vollmers, Christopher — University of California Santa Cruz
- Study coordinator: Vollmers, Christopher
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.