Making Deep Brain Stimulation Work Better for Parkinson's Disease
Spatiotemporal Optimization of Deep Brain Stimulation for Parkinson's Disease
This project aims to make deep brain stimulation (DBS) more effective for people with Parkinson's disease by customizing the treatment to their specific symptoms.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Minnesota NIH-funded |
| Lab location | 1 site (Minneapolis, United States) |
| Project ID | NIH-11127618 on NIH RePORTER |
What this research studies
For people with Parkinson's disease, deep brain stimulation (DBS) can help manage movement problems. This project wants to understand how different settings of DBS affect the brain's motor control network. Researchers will look at how these settings change brain activity at a very detailed level and how they improve specific Parkinson's symptoms like tremor or stiffness. The goal is to develop smart ways to adjust DBS in real-time, making the therapy more personalized and effective for each patient's unique needs.
Who could benefit from this research
Good fit: Patients with Parkinson's disease who are currently receiving or are candidates for deep brain stimulation therapy would be the focus of this research.
Not a fit: Patients without Parkinson's disease or those for whom deep brain stimulation is not a suitable treatment may not directly benefit from this specific research.
Why it matters
Potential benefit: If successful, this work could lead to more precise and personalized deep brain stimulation treatments, offering better control over Parkinson's disease symptoms.
How similar studies have performed: Deep brain stimulation is an established therapy for Parkinson's disease, but this project explores novel ways to optimize its settings for individual symptoms.
Where this research is happening
Minneapolis, United States
- University of Minnesota — Minneapolis, United States (Active)
Researchers
- Principal investigator: Johnson, Matthew Douglas — University of Minnesota
- Study coordinator: Johnson, Matthew Douglas
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.