Lung Cancer Genes in Patients of African Ancestry
Understanding lung cancer genomics in patients of African ancestry
This research looks at the genetic makeup of lung tumors in people of African ancestry to find better ways to treat their cancer.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Sloan-Kettering Inst Can Research NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-11128761 on NIH RePORTER |
What this research studies
Lung cancer is a major health concern for African Americans, and we know that patients of non-European ancestry often don't receive the same advanced genetic testing or targeted treatments. This project aims to understand if there are unique genetic differences in lung cancers among people of African ancestry that could explain some of these disparities. By studying tumor samples, we hope to identify specific genetic changes that might respond to different treatments. This could lead to more personalized and effective care for this patient group.
Who could benefit from this research
Good fit: Ideal candidates for this research would be patients of African ancestry diagnosed with lung cancer whose tumor samples could contribute to understanding genetic differences.
Not a fit: Patients without lung cancer or those of non-African ancestry may not directly benefit from the specific findings of this research.
Why it matters
Potential benefit: If successful, this work could help doctors choose more effective, targeted treatments for lung cancer in patients of African ancestry, potentially improving their survival.
How similar studies have performed: Preliminary analyses using real-world data suggest differences in targetable alterations, building on some previous studies but exploring new aspects of ancestry and smoking effects.
Where this research is happening
New York, United States
- Sloan-Kettering Inst Can Research — New York, United States (Active)
Researchers
- Principal investigator: Zhang, Jian — Sloan-Kettering Inst Can Research
- Study coordinator: Zhang, Jian
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.