Lowering nicotine in smoked tobacco products in New Zealand

Assessing the real-world impact of a low nicotine product standard for smoked tobacco in New Zealand

NIH-funded research Wake Forest University Health Sciences · NIH-11382647

This project looks at how cutting nicotine in cigarettes affects adults who smoke daily in New Zealand over time.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionWake Forest University Health Sciences NIH-funded
Lab location1 site (Winston-Salem, United States)
Project IDNIH-11382647 on NIH RePORTER

What this research studies

You would join a group of about 1,500 adults who smoke daily or nearly daily and be followed across the period around a national nicotine-lowering policy. You'll complete online surveys, give biological samples for exposure biomarkers, have basic health measurements, and take part in interviews about your experiences. The team will also review medical records to track health and quit attempts. The study uses these mixed methods to see how smoking behavior, exposure, and well-being change before and after the policy.

Who could benefit from this research

Good fit: Adults (21 years or older) who smoke daily or nearly daily and live in New Zealand, and who are willing to complete surveys, provide samples, and share health records, are the ideal participants.

Not a fit: People who do not smoke, who smoke only occasionally, are under 21, or live outside New Zealand would not be eligible or likely to benefit directly from participating.

Why it matters

Potential benefit: If successful, this work could show whether lowering nicotine in smoked tobacco leads to less smoking, lower toxic exposure, and more quitting, supporting policies that protect smokers' health.

How similar studies have performed: Randomized trials of very low nicotine cigarettes have shown reduced smoking and dependence, but national, real-world effects under a mandated product standard are largely untested.

Where this research is happening

Winston-Salem, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.