Lowering heart failure risk for people with diabetes and low income
Official title: Understanding and addressing risks of low socioeconomic status and diabetes for heart failure
Funded at Johns Hopkins University · NIH-11134439 · Data updated 2026-11-12
This project brings problem-solving training, community health workers, and local support to people with diabetes, obesity, and low income who have early heart changes to help improve fitness, control risk factors, and feel better.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Johns Hopkins University NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project start | September 24, 2021 |
| Project end | June 30, 2027 |
| Funding year | 2025 |
| Award (this year) | $668,225 |
| NIH project number | 5P50MD017348-05 |
| Project ID | NIH-11134439 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults who have diabetes, obesity, low socioeconomic status, and evidence of early cardiac dysfunction are the most likely candidates for this work.
✕Less likely to help
People without diabetes or low income, or those who already have advanced heart failure, are unlikely to be included or to receive direct benefit from this project.
What this research studies
I would be randomly assigned to get problem-solving training, support from a community health worker, and help connecting with community facilities to change my lifestyle, or to continue with usual care. About 350 people with diabetes, obesity, low socioeconomic status, and early signs of heart dysfunction will join the trial. The team will measure fitness, blood sugar and other risk factors, blood markers of heart injury and fibrosis, and quality of life over time. They will also analyze electronic medical records to understand neighborhood differences in heart failure risk and to find clinical targets for future interventions.
Why it matters
Potential benefit: If successful, this approach could improve fitness, tighten control of risk factors, and reduce future heart failure risk while improving quality of life.
How similar studies have gone: Previous work shows problem-solving training and community health workers can improve diabetes care and lifestyle change, but they have not been widely tested specifically to prevent heart failure.
Where this research is happening
-
Johns Hopkins University
Baltimore, United States Active
Researchers
- Principal investigator: Ndumele, Chiadi E — Johns Hopkins University
- Study coordinator: Ndumele, Chiadi E
Related research
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Exploring how low socioeconomic status and diabetes affect heart failure risk
This study is looking at how being low-income and having diabetes can affect your heart health, especially for people from different racial and ethnic backgrounds, and it will involve 350 participants trying out helpful programs to improve their health and lifestyle.
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This study is working on a special device that helps monitor fluid levels in people with heart failure, especially those with certain heart conditions or who have had heart transplants, to make sure they get the best care possible.
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This study is working on a smart way to predict who might develop type 1 diabetes by looking at certain health markers over time, so that people at risk can be identified and helped earlier.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.