Lower-body heat therapy for long COVID recovery

Heat Therapy for the treatment of post-acute COVID-19 syndrome

['FUNDING_R01'] · UNIVERSITY OF NEBRASKA OMAHA · NIH-11181611

This project will try home-based lower-body heat therapy to help middle-aged and older adults with long COVID improve daily function and cardiovascular/metabolic health.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF NEBRASKA OMAHA (nih funded)
Locations1 site (OMAHA, UNITED STATES)
Trial IDNIH-11181611 on ClinicalTrials.gov

What this research studies

If you join, you'll be randomly assigned to one of three groups and asked to use a lower-body heat device at home or follow a comparison plan. The researchers will track safety, how well people stick with the program, and changes in the ability to do everyday activities and physical tests. They will also collect blood and vascular measurements to see if metabolism and heart-related markers improve. The study focuses on late middle-age and older adults who continue to have symptoms after COVID-19.

Who could benefit from this research

Good fit: Adults with post-acute sequelae of SARS-CoV-2 infection (long COVID), especially late middle-aged and older individuals who have ongoing functional limitations, are the ideal candidates.

Not a fit: People without long COVID, those with unstable or serious cardiovascular conditions, or anyone whose symptoms worsen with heat or exertion may not benefit and could be excluded.

Why it matters

Potential benefit: If successful, this could offer a simple at-home therapy to improve function and reduce cardiovascular and metabolic risks for people with long COVID.

How similar studies have performed: Some studies of whole-body heat or sauna therapy have shown cardiovascular and metabolic benefits, but using lower-body, home-based heat specifically for long COVID is largely new and untested.

Where this research is happening

OMAHA, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.