NIH-funded research Sbir 2 grant

Low SWaP wearable detector for phosgene safety

Official title: Low SWaP Phosgene Clip Detector

Funded at Intelligent Optical Systems, INC. · NIH-11253861 · Data updated 2026-11-12

A wearable, low size-and-power detector will continuously monitor for phosgene to protect workers in chemical industries.

Quick facts

Grant typeSbir 2 grant
Study typeNIH-funded research
Funding institutionIntelligent Optical Systems, INC.
NIH-funded
Lab location1 site (Gardena, UNITED STATES)
Project startSeptember 1, 2026
Project endAugust 31, 2028
Funding year2025
Award (this year)$520,010
NIH project number2R44OH012575-02
Project IDNIH-11253861 on NIH RePORTER

Who could benefit from this research

Could help

Not applicable here since this is a device for workers in high-risk industries rather than a patient population.

Less likely to help

N/A for patient-focused benefit since the grant targets workplace safety technology rather than a medical treatment.

What this research studies

This grant aims to create a compact, lightweight sensor that can be worn by workers to detect phosgene at very low levels and warn them instantly through sound, light, or vibration. It builds on Phase I results that reached 0.1 ppm detection and 16 days of operation, and Phase II plans to push detection to 0.02 ppm and produce a wearable prototype. The device will be fully characterized, tested in controlled settings, and validated in simulated manufacturing environments to ensure reliability and real-time alerts. The goal is to reduce exposure risk and prevent harm by enabling immediate protective actions.

Why it matters

Potential benefit: If successful, workers will have reliable, real-time phosgene detection and alerts, reducing exposure and preventing injuries.

How similar studies have gone: Prior colorimetric badges exist but have limited detection and lifetime; the proposed wearable aims for substantially better performance.

Where this research is happening

  • Intelligent Optical Systems, INC.
    Gardena, United States
    Active

Researchers

  • Principal investigator: Zhang, Lihua — Intelligent Optical Systems, INC.
  • Study coordinator: Zhang, Lihua

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.