Longitudinal study of Plasmodium vivax relapses in Central Africa
Official title: A longitudinal cohort study of Plasmodium vivax relapses in Central Africa
Funded at Drexel University · NIH-11579103 · Data updated 2026-11-12
This study follows people in Central Africa to understand how Plasmodium vivax relapses affect illness and transmission.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Drexel University NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project start | August 25, 2025 |
| Project end | July 31, 2027 |
| Funding year | 2026 |
| Award (this year) | $56,484 |
| NIH project number | 3R21AI190606-02S1 |
| Project ID | NIH-11579103 on NIH RePORTER |
Who could benefit from this research
✓Could help
Individuals living in Central Africa who have or are suspected to have Plasmodium vivax infection and are available for follow-up.
✕Less likely to help
Individuals without suspected Pv infection or those unable to participate in long-term follow-up may not benefit.
What this research studies
Researchers will enroll participants in Central Africa and track Pv relapse episodes over time, using blood tests and clinical data. The study will explore how Pv relapses occur in the context of Duffy negativity and widespread malaria treatment practices. Findings could inform better diagnosis, treatment decisions, and control strategies for vivax malaria in African settings.
Why it matters
Potential benefit: It could lead to improved prevention and treatment approaches for vivax malaria in Central Africa.
How similar studies have gone: Prior research suggests Pv relapses are common and clinically relevant in various settings, but Africa-specific data are limited, making this study potentially impactful.
Where this research is happening
-
Drexel University
Philadelphia, United States Active
Researchers
- Principal investigator: Lo, Eugenia — Drexel University
- Study coordinator: Lo, Eugenia
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.