NIH-funded research R01 grant

Longitudinal Changes in Prescription Drug Misuse Among Adolescents and Young Adults

Official title: Longitudinal Changes in Prescription Drug Misuse and Polysubstance Use in Adolescents and Young Adults

Funded at Texas State University · NIH-11380827 · Data updated 2026-11-12

A long-term study following adolescents and young adults to understand how and why prescription drug misuse and use of multiple substances change over time.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionTexas State University
NIH-funded
Lab location1 site (San Marcos, United States)
Project startJune 1, 2017
Project endJuly 31, 2027
Funding year2026
Award (this year)$306,204
NIH project number5R01DA043691-07
Project IDNIH-11380827 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates are adolescents and young adults (roughly ages 12–30) who have or may be at risk for prescription drug misuse or polysubstance use.

Less likely to help

Young people not exposed to prescription medications or those outside the AYAs age range may not directly benefit.

What this research studies

This project tracks people aged roughly 12 to 30 to map how prescription drug misuse begins, evolves, and relates to other substances over years. Using large national datasets, it will examine patterns by age, birth cohort, and time period to identify when risk is highest and what factors drive polysubstance use. The goal is to inform policies and create better screening and intervention strategies for AYAs at risk. Participants may contribute by providing survey data through established national studies and may benefit indirectly from improved prevention tools.

Why it matters

Potential benefit: If successful, findings could lead to earlier identification of at-risk AYAs and more effective screening and intervention efforts for prescription drug misuse.

How similar studies have gone: Prior work has mapped prevalence and patterns, but this project adds longitudinal APC analyses and polysubstance considerations.

Where this research is happening

  • Texas State University
    San Marcos, United States
    Active

Researchers

  • Principal investigator: Schepis, Ty Stephen — Texas State University
  • Study coordinator: Schepis, Ty Stephen

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.