Long-term tracking of kidney and heart health in children and teens with chronic kidney disease
Official title: Chronic Kidney Disease in Children (CKiD V)
Funded at Children's Mercy Hosp (Kansas City, Mo) · NIH-11136308 · Data updated 2026-11-12
Tracking children and teens with chronic kidney disease to learn how kidney function and heart health change as they grow into young adults.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Children's Mercy Hosp (Kansas City, Mo) NIH-funded |
| Lab location | 1 site (Kansas City, United States) |
| Project start | September 30, 2003 |
| Project end | July 31, 2028 |
| Funding year | 2025 |
| Award (this year) | $1,034,674 |
| NIH project number | 5U01DK066143-23 |
| Project ID | NIH-11136308 on NIH RePORTER |
Who could benefit from this research
✓Could help
Children and adolescents with chronic kidney disease, especially teens aged about 14–17 who are transitioning toward adult care, are ideal candidates.
✕Less likely to help
People without chronic kidney disease or those not in the pediatric/young-adult age range are unlikely to receive direct benefit from this project.
What this research studies
If you join, the team will continue following kids already in CKiD and will invite teens aged 14–17 to join so we can watch kidney function and heart health as you move into adulthood. Most data can be collected remotely through home or local lab visits for vitals and blood tests, and by pulling relevant information from your electronic health record. You can report symptoms and other information through secure web or mobile forms, and the team will combine clinical markers with social and health data to build prediction tools. The project links with other pediatric kidney cohorts to improve comparisons and learnings.
Why it matters
Potential benefit: Results could help identify kids at higher risk of faster kidney decline so doctors can target monitoring and early treatment.
How similar studies have gone: Earlier CKiD and related pediatric kidney cohorts have provided important findings about childhood CKD, while the combination of remote data collection and machine-learning prediction in teens is a newer extension of that work.
Where this research is happening
-
Children's Mercy Hosp (Kansas City, Mo)
Kansas City, United States Active
Researchers
- Principal investigator: Warady, Bradley Alan — Children's Mercy Hosp (Kansas City, Mo)
- Study coordinator: Warady, Bradley Alan
Related research
Other NIH-funded projects on the same topics.
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Personalized CKD-MBD care using systems biology and AI
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This project tests a new way to prevent dangerous diabetic ketoacidosis in people with type 1 diabetes and chronic kidney disease who are using SGLT inhibitors, by tracking ketones in real time and combining glucose-keton data for safer therapy.
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Chronic Kidney Disease in Children: following young people as they grow up with CKD
A long-term study in kids with chronic kidney disease tracks kidney function and heart health as they transition into adulthood.
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Chronic Kidney Disease in Children follow-up study
A long-term study that follows kids with kidney disease as they grow into young adults, collecting health data from home and official records.
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This grant looks at why some children who have malaria develop kidney injury and later chronic kidney disease, focusing on how severe malaria affects the kidneys over time.
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Boosting self-care and physical activity for older adults with chronic kidney disease
This program helps older adults with chronic kidney disease build the skills, confidence, and motivation to be more physically active.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.