Long-term outcomes after childhood out-of-hospital cardiac arrest

P-ICECAP Extended

NIH-funded research Hugo W. Moser Res Inst Kennedy Krieger · NIH-11298962

This project follows children who survived cardiac arrest outside the hospital to learn how they function and how their families cope over several years.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionHugo W. Moser Res Inst Kennedy Krieger NIH-funded
Lab location1 site (Baltimore, United States)
Project IDNIH-11298962 on NIH RePORTER

What this research studies

You (or your child) would be re-contacted if they survived an out-of-hospital cardiac arrest and took part in prior pediatric cardiac arrest trials so clinicians can collect information at school age and beyond. The team will use standardized tests and caregiver questionnaires to measure children's adaptive functioning, cognitive and developmental skills, and family burden. Researchers will build on data from the multi-center THAPCA-OH trial and the P-ICECAP project to compare outcomes by age, disability level, and treatments received. Follow-up may include in-person visits at participating centers, remote assessments, and review of prior medical records.

Who could benefit from this research

Good fit: Children who survived an out-of-hospital cardiac arrest (especially those previously enrolled in the THAPCA-OH or P-ICECAP studies) and their caregivers.

Not a fit: Children whose cardiac arrest occurred in the hospital, those not reachable or unwilling to join follow-up, or families unable to travel to participating centers are unlikely to be included and may not receive direct benefit.

Why it matters

Potential benefit: If successful, this work could help clinicians identify children who need long-term rehabilitation or support and guide families to resources that reduce caregiver burden.

How similar studies have performed: Earlier multi-center work (THAPCA-OH) described one-year outcomes showing substantial disability and family burden, but long-term follow-up beyond one year is limited so this extension fills an important gap.

Where this research is happening

Baltimore, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Acquired brain injury
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.