Long-term osteoporosis treatment strategies
Official title: Long-Term Approaches to Treating Osteoporosis
Funded at Berkeley Madonna, INC. · NIH-11159522 · Data updated 2026-11-12
This project aims to find better ways to switch and combine osteoporosis medicines so older adults can lower their long-term fracture risk.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Berkeley Madonna, INC. NIH-funded |
| Lab location | 1 site (Albany, UNITED STATES) |
| Project start | September 30, 2023 |
| Project end | May 31, 2027 |
| Funding year | 2025 |
| Award (this year) | $179,184 |
| NIH project number | 5R01AG081466-03 |
| Project ID | NIH-11159522 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates would be adults with diagnosed osteoporosis—especially people aged 65 and older or those with prior fragility fractures—who are on or considering osteoporosis medications.
✕Less likely to help
People who are younger with low fracture risk, do not have osteoporosis, or who cannot take osteoporosis drugs for medical reasons are less likely to benefit directly.
What this research studies
You will see researchers comparing different sequences of commonly used osteoporosis drugs and short-term combination treatments to learn which keep bones stronger and cause fewer side effects. They will look at clinical outcomes such as fractures, bone density, and adverse experiences using data from trials, clinical records, or new patient visits. The work focuses on practical treatment plans people can follow over many years rather than one-off courses of medicine. If you have osteoporosis, the results could help your doctor choose safer, longer-lasting medication strategies.
Why it matters
Potential benefit: If successful, this work could produce clearer, safer lifelong medication plans that reduce fracture risk for people with osteoporosis.
How similar studies have gone: Some individual drug trials and short-term combination studies have shown benefits, but long-term sequencing and combination strategies remain relatively untested and are a newer area of study.
Where this research is happening
-
Berkeley Madonna, INC.
Albany, United States Active
Researchers
- Principal investigator: Nayak, Smita — Berkeley Madonna, INC.
- Study coordinator: Nayak, Smita
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.