Long-term follow-up of babies born extremely preterm with early lung disease
Neonatal Research Network Data Coordinating Center (DCC) 2023-2028
This project follows children who were born extremely preterm and took part in a hydrocortisone trial to learn how their breathing and development are doing at about 5 years old.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Research Triangle Institute NIH-funded |
| Lab location | 1 site (Research Triangle Park, United States) |
| Project ID | NIH-11310029 on NIH RePORTER |
What this research studies
If my child was in the original hydrocortisone trial for bronchopulmonary dysplasia (BPD), researchers will bring them back at about 5 years corrected age for in-person breathing tests, developmental and school-readiness evaluations, and parent questionnaires. The follow-up builds on detailed newborn and early-childhood data already collected by the Neonatal Research Network and uses standardized tests and medical record review. These visits aim to show how early lung disease and the treatment relate to everyday breathing, learning, and need for services at early school age. Study visits are organized through the Network's clinical sites and coordinated by the Data Coordinating Center.
Who could benefit from this research
Good fit: Children who were enrolled in the original NICHD Neonatal Research Network hydrocortisone for BPD trial and are approaching about 5 years corrected age are ideal candidates.
Not a fit: Children who were not part of the original trial, are outside the target age window, or cannot attend the follow-up visits are unlikely to directly benefit from participation.
Why it matters
Potential benefit: If successful, the results could clarify whether early hydrocortisone treatment changes breathing, developmental skills, and the supports children need at school age.
How similar studies have performed: Previous Neonatal Research Network follow-up studies have provided important long-term outcome data, but long-term effects of neonatal hydrocortisone on school-age respiratory and developmental outcomes remain uncertain.
Where this research is happening
Research Triangle Park, United States
- Research Triangle Institute — Research Triangle Park, United States (Active)
Researchers
- Principal investigator: Das, Abhik — Research Triangle Institute
- Study coordinator: Das, Abhik
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.