Long-term follow-up for patients who participated in a stroke prevention trial
Long-Term Observational Extension of Participants in the CREST-2 Randomized Clinical Trial
This study is looking at how well certain medical treatments and surgeries help prevent strokes over the long run, and it's for patients who have already been part of the CREST-2 trial, as we check in with them through virtual visits and home assessments to keep their health on track.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Mayo Clinic Jacksonville NIH-funded |
| Lab location | 1 site (Jacksonville, United States) |
| Project ID | NIH-10925193 on NIH RePORTER |
What this research studies
This research focuses on the long-term effects of intensive medical management and surgical procedures like carotid endarterectomy and stenting on stroke prevention. It involves monitoring patients who have previously participated in the CREST-2 trial to assess the effectiveness of these treatments over time. Patients will be followed up through telehealth visits and home health assessments to ensure their vascular risk factors are managed effectively. The goal is to determine the real-world effectiveness of these interventions in preventing strokes.
Who could benefit from this research
Good fit: Ideal candidates are individuals who have previously participated in the CREST-2 trial and are at risk for stroke due to carotid artery disease.
Not a fit: Patients who have not participated in the CREST-2 trial or do not have carotid artery disease may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for stroke prevention and better management of vascular health in patients.
How similar studies have performed: Previous studies have shown success in managing vascular risk factors through intensive medical management, making this approach promising.
Where this research is happening
Jacksonville, United States
- Mayo Clinic Jacksonville — Jacksonville, United States (Active)
Researchers
- Principal investigator: Meschia, James F — Mayo Clinic Jacksonville
- Study coordinator: Meschia, James F
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.