Long-term effects of COVID-19 and MIS-C in children

Pediatric severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and Multisystem Inflammatory Syndrome in Children (MIS-C) long-term follow-up

NIH-funded research Leidos Biomedical Research, INC. · NIH-10506018

This study is looking at how COVID-19 affects the long-term health of kids and young adults up to 21 years old, including those who had mild or no symptoms, to better understand their recovery and any ongoing health concerns.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionLeidos Biomedical Research, INC. NIH-funded
Lab location1 site (Frederick, United States)
Project IDNIH-10506018 on NIH RePORTER

What this research studies

This research investigates the long-term health effects of SARS-CoV-2 infection, including both symptomatic and asymptomatic cases, in children and young adults aged 0-21 years. It focuses on understanding the clinical outcomes associated with COVID-19 and Multisystem Inflammatory Syndrome in Children (MIS-C). By observing a diverse group of pediatric patients over time, the study aims to gather valuable data on their recovery, immune responses, and any lasting health issues they may face. This information will help inform future treatments and care strategies for affected children.

Who could benefit from this research

Good fit: Ideal candidates for this research include children and young adults aged 0-21 who have experienced SARS-CoV-2 infection, whether symptomatic or asymptomatic.

Not a fit: Patients who have not been infected with SARS-CoV-2 or who are outside the age range of 0-21 years may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved understanding and management of long-term health issues related to COVID-19 and MIS-C in children.

How similar studies have performed: Other research has shown promising results in understanding the long-term effects of COVID-19 in adults, suggesting that similar approaches in pediatric populations may also yield valuable insights.

Where this research is happening

Frederick, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.