Long-lasting injectable naltrexone for opioid addiction treatment

Injectable naltrexone 2-month depot formulations

NIH-funded research Purdue University · NIH-10756971

This study is working on a new, easy-to-use injection of naltrexone that lasts for two months to help people with opioid addiction stick to their treatment and stay safe from overdose.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionPurdue University NIH-funded
Lab location1 site (West Lafayette, United States)
Project IDNIH-10756971 on NIH RePORTER

What this research studies

This research focuses on developing a new formulation of naltrexone, an effective medication for treating opioid addiction and preventing overdose. The goal is to create a 2-month injectable version that is easier for patients to use, addressing the common issue of noncompliance with current treatment methods. By utilizing advanced drug delivery systems, the research aims to enhance the medication's effectiveness and patient adherence. The project will involve rigorous testing to ensure the new formulation is safe and effective for long-term use.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals with opioid use disorders who are seeking effective treatment options.

Not a fit: Patients who are not struggling with opioid addiction or those who have contraindications to naltrexone may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could provide a more convenient and effective treatment option for individuals struggling with opioid addiction.

How similar studies have performed: Previous research has shown success with long-acting formulations of medications for addiction treatment, indicating potential for this approach.

Where this research is happening

West Lafayette, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Centers for Disease ControlCenters for Disease Control and PreventionUnited States Centers for Disease Control
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.