Long-lasting delivery of Tizanidine to treat severe muscle stiffness
Sustained Delivery of Tizanidine for Maintenance Treatment of Moderate to Severe Spasticity
This study is working on a new way to deliver Tizanidine, a medicine that helps with muscle tightness and spasms, to make it easier for people with conditions like cerebral palsy, multiple sclerosis, and spinal cord injuries to manage their symptoms and feel better.
Quick facts
| Grant type | Sbir 2 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Delpor, INC. NIH-funded |
| Lab location | 1 site (South San Francisco, United States) |
| Project ID | NIH-10490906 on NIH RePORTER |
What this research studies
This research focuses on developing a method for sustained delivery of Tizanidine, a medication used to treat spasticity, which is characterized by increased muscle tone and involuntary muscle contractions. The approach aims to provide a more consistent and effective treatment for patients suffering from conditions like cerebral palsy, multiple sclerosis, and spinal cord injuries, who often experience inadequate symptom relief with current treatment methods. By reducing the frequency of medication administration and minimizing side effects, this research seeks to improve the quality of life for patients with severe spasticity.
Who could benefit from this research
Good fit: Ideal candidates for this research include adults and children with moderate to severe spasticity due to conditions such as cerebral palsy, multiple sclerosis, or spinal cord injuries.
Not a fit: Patients who do not experience spasticity or have mild forms of muscle stiffness may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could significantly enhance the management of spasticity, leading to improved daily functioning and quality of life for affected patients.
How similar studies have performed: Previous research has shown that sustained delivery systems for medications can improve treatment outcomes, indicating potential success for this novel approach.
Where this research is happening
South San Francisco, United States
- Delpor, INC. — South San Francisco, United States (Active)
Researchers
- Principal investigator: Watkins, Gregory — Delpor, INC.
- Study coordinator: Watkins, Gregory
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.