NIH-funded research R01 grant

Long-lasting delivery of HIV prevention medications

Official title: Systemic Sustained Release Delivery of Antiretroviral Agents for HIV Prevention

Funded at Oak Crest Institute of Science · NIH-10854871 · Data updated 2026-11-12

This study is testing a new way to deliver HIV prevention medications that could make it easier for people to stay protected, with options for taking them less often, like once a month or even less frequently.

More HIV Prevention research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionOak Crest Institute of Science
NIH-funded
Lab location1 site (Monrovia, United States)
Project startJuly 15, 2021
Project endJune 30, 2026
Funding year2024
Award (this year)$736,698
NIH project number5R01AI162151-04
Project IDNIH-10854871 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are individuals at high risk of contracting HIV who may benefit from long-acting preventive treatments.

Less likely to help

Patients who are already HIV positive or those who do not have risk factors for HIV infection may not receive benefit from this research.

What this research studies

This research focuses on developing a new method for delivering antiretroviral medications to prevent HIV infection. By creating long-acting formulations that require less frequent dosing, the study aims to improve adherence to HIV prevention strategies. Patients will benefit from a more convenient and effective way to protect themselves from HIV, as the new delivery system could potentially allow for monthly or even less frequent dosing. The research involves clinical evaluations of these new formulations to ensure their safety and effectiveness.

Why it matters

Potential benefit: If successful, this research could provide a more effective and convenient method for HIV prevention, significantly reducing new infection rates.

How similar studies have gone: Previous research has shown success with long-acting formulations in other areas of medicine, indicating potential for similar advancements in HIV prevention.

Where this research is happening

  • Oak Crest Institute of Science
    Monrovia, United States
    Active

Researchers

  • Principal investigator: Baum, Marc Michael — Oak Crest Institute of Science
  • Study coordinator: Baum, Marc Michael

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.