NIH-funded research R01 grant

Loneliness, social isolation, and alcohol/drug use over time in U.S. adults

Official title: Trajectories of Isolation and (A)Loneliness with AOD Use, 2019-2027: A National Egocentric Network Study of US Adults

Funded at Rand Corporation · NIH-11392985 · Data updated 2026-11-12

This project follows U.S. adults ages 30–80 over eight years to see how loneliness, social connections, and alcohol or drug use change together.

More Loneliness research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionRand Corporation
NIH-funded
Lab location1 site (Santa Monica, United States)
Project startMay 1, 2024
Project endMarch 31, 2029
Funding year2026
Award (this year)$631,162
NIH project number5R01AA030890-03
Project IDNIH-11392985 on NIH RePORTER

Who could benefit from this research

Could help

Ideal participants are U.S. adults aged 30–80, including those who drink alcohol, use cannabis or other drugs, or who feel socially isolated or lonely.

Less likely to help

People under 30, those living outside the U.S., or anyone seeking immediate clinical treatment may not receive direct benefit from this observational project.

What this research studies

You would be followed each year for eight consecutive years and asked about your social connections, feelings of loneliness and the newer idea of "aloneliness," plus any alcohol, cannabis, or other drug use. The study uses surveys and egocentric network questions that ask who you regularly interact with and how close you feel to them. You would also answer standard questions about depression and anxiety so researchers can look at mental health as a link between social connection and substance use. The project aims to create the largest long-term dataset on adult social connection and substance use to guide prevention and care.

Why it matters

Potential benefit: If successful, this work could help identify people at higher risk and inform prevention programs or clinical strategies that reduce harmful alcohol and drug use tied to loneliness and isolation.

How similar studies have gone: Prior research has linked loneliness to substance use, but long-term egocentric network approaches and the concept of aloneliness are relatively new, so this project is a novel extension of existing findings.

Where this research is happening

  • Rand Corporation
    Santa Monica, United States
    Active

Researchers

  • Principal investigator: Pollard, Michael Sean — Rand Corporation
  • Study coordinator: Pollard, Michael Sean

Related research

Other NIH-funded projects on the same topics.

  • Social virtual reality to tackle loneliness in older men with HIV

    A new virtual reality program designed for older men living with HIV to connect with others and reduce loneliness, with the goal of improving health and daily well‑being.

    NIH research University of Pennsylvania · Philadelphia, United States · NIH-11470637

  • ADRD spousal caregivers: real-time loneliness and immune links

    A real-world study will follow 300 spouses caring for someone with Alzheimer’s disease or related dementias to understand how loneliness, social isolation, and daily stress relate to immune and cellular aging.

    NIH research Rice University · Houston, United States · NIH-11457084

  • Understanding loneliness in stroke survivors to improve care

    A study will identify different loneliness risk profiles in adults who had a stroke or TIA to help tailor support and interventions.

    NIH research Columbia University Health Sciences · New York, United States · NIH-11450888

  • New daily loneliness indicators and aging outcomes

    Researchers are studying how day-to-day loneliness affects aging and health in adults, to uncover how loneliness might speed up biological aging and functional decline.

    NIH research Arizona State University-Tempe Campus · Scottsdale, United States · NIH-11434934

  • Understanding how the brain and thinking shape loneliness in adults

    This grant studies how brain processes and thoughts create loneliness in adults and could help develop ways to reduce loneliness and its health risks.

    NIH research Icahn School of Medicine at Mount Sinai · New York, United States · NIH-11401424

  • How loneliness and culture shape risky drinking patterns

    This grant explores why loneliness and cultural context influence risky drinking, with goals to help people in diverse communities understand and reduce problematic alcohol use.

    NIH research University of Houston · Houston, United States · NIH-11396959

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.