Loneliness, social isolation, and alcohol/drug use over time in U.S. adults

Trajectories of Isolation and (A)Loneliness with AOD Use, 2019-2027: A National Egocentric Network Study of US Adults

NIH-funded research Rand Corporation · NIH-11392985

This project follows U.S. adults ages 30–80 over eight years to see how loneliness, social connections, and alcohol or drug use change together.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionRand Corporation NIH-funded
Lab location1 site (Santa Monica, United States)
Project IDNIH-11392985 on NIH RePORTER

What this research studies

You would be followed each year for eight consecutive years and asked about your social connections, feelings of loneliness and the newer idea of "aloneliness," plus any alcohol, cannabis, or other drug use. The study uses surveys and egocentric network questions that ask who you regularly interact with and how close you feel to them. You would also answer standard questions about depression and anxiety so researchers can look at mental health as a link between social connection and substance use. The project aims to create the largest long-term dataset on adult social connection and substance use to guide prevention and care.

Who could benefit from this research

Good fit: Ideal participants are U.S. adults aged 30–80, including those who drink alcohol, use cannabis or other drugs, or who feel socially isolated or lonely.

Not a fit: People under 30, those living outside the U.S., or anyone seeking immediate clinical treatment may not receive direct benefit from this observational project.

Why it matters

Potential benefit: If successful, this work could help identify people at higher risk and inform prevention programs or clinical strategies that reduce harmful alcohol and drug use tied to loneliness and isolation.

How similar studies have performed: Prior research has linked loneliness to substance use, but long-term egocentric network approaches and the concept of aloneliness are relatively new, so this project is a novel extension of existing findings.

Where this research is happening

Santa Monica, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.