Linking life stages, biological measures, and digital health data to understand heart and lung health
Integrating lifecourse approaches, biologic and digital phenotypes in support of heart and lung disease epidemiologic research
['FUNDING_U01'] · HARVARD UNIVERSITY D/B/A HARVARD SCHOOL OF PUBLIC HEALTH · NIH-11026395
This project combines health and pregnancy histories, biological samples, and digital data from women and their families to find patterns that predict heart and lung problems.
Quick facts
| Phase | ['FUNDING_U01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | HARVARD UNIVERSITY D/B/A HARVARD SCHOOL OF PUBLIC HEALTH (nih funded) |
| Locations | 1 site (BOSTON, UNITED STATES) |
| Trial ID | NIH-11026395 on ClinicalTrials.gov |
What this research studies
You would be asked to share your health and reproductive history, provide biological samples, and allow collection of digital health data (like wearable or mobile information). The work brings together three long-running groups—the Nurses' Health Study II, Nurses' Health Study 3, and the Growing Up Today Study—to follow people across the life course. Researchers link mothers, their adult children, and grandmothers where available to look for early-life and pregnancy factors that affect heart and lung risk. Because participants are spread across the U.S. and include many African American and Hispanic people, the findings aim to reflect diverse communities.
Who could benefit from this research
Good fit: Ideal participants are women enrolled in NHS-II or NHS3 and their adult offspring in GUTS, especially pregnant people, mothers, and family members willing to share health, sample, and digital data.
Not a fit: People who are not enrolled in these cohorts, who live outside the U.S., or who do not want to share biological samples or digital health data would not be able to participate or benefit directly.
Why it matters
Potential benefit: If successful, this work could reveal early signs and risk factors that help prevent or detect heart and lung disease sooner.
How similar studies have performed: Large cohorts like the Nurses' Health Studies have previously linked pregnancy and early-life factors to later heart and lung risks, though combining multigenerational data with digital phenotypes is a newer approach.
Where this research is happening
BOSTON, UNITED STATES
- HARVARD UNIVERSITY D/B/A HARVARD SCHOOL OF PUBLIC HEALTH — BOSTON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: CHAVARRO, JORGE EDUARDO — HARVARD UNIVERSITY D/B/A HARVARD SCHOOL OF PUBLIC HEALTH
- Study coordinator: CHAVARRO, JORGE EDUARDO
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.