Linking clinical trials to real-world patient data
Enhancing evidence generation by linking randomized clinical trials (RCTs) to real world data (RWD)
['FUNDING_U01'] · BRIGHAM AND WOMEN'S HOSPITAL · NIH-10455527
This study is looking to make heart health clinical trials better by using real-life health information, so the results can be more helpful and relevant for all patients.
Quick facts
| Phase | ['FUNDING_U01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | BRIGHAM AND WOMEN'S HOSPITAL (nih funded) |
| Locations | 1 site (BOSTON, UNITED STATES) |
| Trial ID | NIH-10455527 on ClinicalTrials.gov |
What this research studies
This research aims to improve the effectiveness of clinical trials by connecting them with real-world data, such as electronic health records and insurance claims. By doing so, it seeks to address common limitations of traditional randomized controlled trials, including missing data and limited follow-up. The project will focus on two specific clinical trials related to heart health, using the linked data to enhance findings and make them more applicable to diverse patient populations. The goal is to develop methods that can improve the reliability and relevance of clinical trial results for patients.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients who have participated in the linked clinical trials or those with heart-related conditions.
Not a fit: Patients who are not involved in the specific clinical trials or do not have heart-related health issues may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more accurate and applicable treatment outcomes for patients based on real-world evidence.
How similar studies have performed: Other research has shown promise in linking clinical trials with real-world data, indicating that this approach could enhance the understanding of treatment effectiveness.
Where this research is happening
BOSTON, UNITED STATES
- BRIGHAM AND WOMEN'S HOSPITAL — BOSTON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: PATORNO, ELISABETTA — BRIGHAM AND WOMEN'S HOSPITAL
- Study coordinator: PATORNO, ELISABETTA
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.