Linking brain imaging and genetic data to understand Alzheimer's disease
Official title: Flexible multivariate models for linking multi-scale connectome and genome data in Alzheimer’s disease and related disorders
Funded at Georgia State University · NIH-11024633 · Data updated 2026-11-12
This study is looking at how we can use brain scans and genetic information together to better understand Alzheimer's disease and help improve diagnosis and treatment for patients.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Georgia State University NIH-funded |
| Lab location | 1 site (Atlanta, United States) |
| Project start | June 1, 2025 |
| Project end | February 28, 2030 |
| Funding year | 2025 |
| Award (this year) | $766,467 |
| NIH project number | 1R01AG090597-01 |
| Project ID | NIH-11024633 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals diagnosed with Alzheimer's disease or related dementias, as well as those at risk due to genetic factors.
✕Less likely to help
Patients with non-neurological conditions or those without any genetic predisposition to Alzheimer's disease may not benefit from this research.
What this research studies
This research investigates how to better analyze and combine brain imaging and genetic data to improve understanding of Alzheimer's disease and related disorders. By using advanced multivariate models, the project aims to uncover complex relationships between neuroimaging and genomic data that are often overlooked. Patients' data will be analyzed in a way that allows for a more integrated view of their condition, potentially leading to more accurate diagnoses and treatment strategies.
Why it matters
Potential benefit: If successful, this research could lead to improved diagnostic tools and treatment options for patients with Alzheimer's disease and related dementias.
How similar studies have gone: Previous research has shown promise in using multivariate approaches to analyze complex data in Alzheimer's studies, indicating potential for success in this novel approach.
Where this research is happening
-
Georgia State University
Atlanta, United States Active
Researchers
- Principal investigator: Calhoun, Vince D — Georgia State University
- Study coordinator: Calhoun, Vince D
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.