LifeBio Memory — an AI-powered, multilingual app to make memory conversations more engaging

LifeBio Memory: Development of a reminiscence therapy online platform with machine learning to increase engagement

NIH-funded research Lifebio INC · NIH-11253813

This project offers an AI voice‑enabled, multilingual app to help older adults with mild cognitive impairment and their caregivers share life stories more easily and feel more connected.

Quick facts

Grant typeSbir 2 grant
Study typeNIH-funded research
Funding institutionLifebio INC NIH-funded
Lab location1 site (Marysville, United States)
Project IDNIH-11253813 on NIH RePORTER

What this research studies

You would use an app that prompts and records life stories, with built‑in AI that can learn and recreate a loved one’s voice to make conversations feel more personal. The team will add Spanish and Korean language support and tailor content for African American users. First, small usability sessions with about 48 people will check how easy and satisfying the app is to use, then a larger randomized feasibility test will look at effects on mood, loneliness, relationship closeness, and quality of life. Caregivers are included so the app is tested in the real-world situations where memory conversations happen.

Who could benefit from this research

Good fit: Ideal participants are older adults with mild cognitive impairment or at risk for it, including English, Spanish, or Korean speakers, and their informal caregivers who are willing to use an app or have someone help them use it.

Not a fit: People with advanced dementia who cannot participate in conversations, those who do not want AI voice cloning, or those without access to a device or support to use the app may not benefit from this project.

Why it matters

Potential benefit: If successful, the app could make reminiscence sessions more engaging and reduce loneliness and depression while improving relationship closeness and quality of life for people with early memory loss and their caregivers.

How similar studies have performed: Reminiscence therapy has shown benefits for mood and social connection in prior research and LifeBio’s earlier tools increased engagement, but the combination of AI voice cloning and multilingual cultural tailoring is new and less tested.

Where this research is happening

Marysville, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.