Leukemia data analysis and biomarker discovery
Biostatistics and Computational Biology
Using advanced data and statistical tools to find markers and guide new treatments for people with leukemia.
Quick facts
| Grant type | P01 program project |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Dana-Farber Cancer Inst NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-11196545 on NIH RePORTER |
What this research studies
This program provides the biostatistics and computational support that helps researchers make sense of data from leukemia patient samples, mouse models, and cell lines. The team uses bioinformatics, algorithms, and rigorous statistics to look for molecular signals that could become diagnostic or treatment markers. They work closely with labs that process samples and with clinical teams to combine lab findings with patient information. The Core also helps share and manage data so discoveries can move toward clinical testing.
Who could benefit from this research
Good fit: People with leukemia who are treated at or enrolled in Dana-Farber or affiliated clinical projects and can provide blood or bone marrow samples are the most likely candidates to contribute.
Not a fit: People without leukemia or those not enrolled at participating centers or not providing specimens are unlikely to gain direct benefit from this core program.
Why it matters
Potential benefit: If successful, this work could identify markers that predict how patients will respond to therapies and speed the development of targeted leukemia treatments.
How similar studies have performed: Other bioinformatics-driven programs have found useful biomarkers and informed drug development, though turning those findings into approved treatments typically takes time.
Where this research is happening
Boston, United States
- Dana-Farber Cancer Inst — Boston, United States (Active)
Researchers
- Principal investigator: Simon, Jeremy M. — Dana-Farber Cancer Inst
- Study coordinator: Simon, Jeremy M.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.