Lengthening the intestine to help patients with Short Bowel Syndrome
Intestinal Lengthening via Distraction Enterogenesis for the Treatment of Short Bowel Syndrome
This study is exploring a new way to help people with Short Bowel Syndrome by gently stretching their remaining small intestine, which could help them absorb more nutrients and reduce the need for expensive treatments.
Quick facts
| Grant type | Sbir 2 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Eclipse Enterogenesis, INC. NIH-funded |
| Lab location | 1 site (Menlo Park, United States) |
| Project ID | NIH-10705620 on NIH RePORTER |
What this research studies
This research investigates a novel approach called distraction enterogenesis, which aims to lengthen the small intestine in patients suffering from Short Bowel Syndrome (SBS). SBS is a serious condition where patients cannot absorb enough nutrients due to significant loss of their small intestine, often from surgeries related to diseases like Crohn's or cancer. The study will involve patients undergoing a procedure that gradually stretches the remaining intestine, potentially allowing for improved nutrient absorption. By focusing on both pediatric and adult populations, the research seeks to provide a new treatment option that could reduce reliance on costly and invasive therapies.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals diagnosed with Short Bowel Syndrome, particularly those who have undergone significant intestinal resections due to conditions like Crohn's disease or cancer.
Not a fit: Patients who have not experienced significant intestinal loss or those with other unrelated gastrointestinal disorders may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could significantly improve the quality of life for patients with Short Bowel Syndrome by restoring their ability to absorb nutrients naturally.
How similar studies have performed: Previous research has shown promising results with distraction enterogenesis in animal models, but this approach is still relatively novel in human applications.
Where this research is happening
Menlo Park, United States
- Eclipse Enterogenesis, INC. — Menlo Park, United States (Active)
Researchers
- Principal investigator: Bessette, Andre — Eclipse Enterogenesis, INC.
- Study coordinator: Bessette, Andre
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.