Learning how malaria and toxoplasmosis parasites communicate inside their cells

Understanding inter-organellar communication in apicomplexan parasites

['FUNDING_OTHER'] · UNIVERSITY OF GEORGIA · NIH-11137015

This project aims to understand how the tiny parts inside parasites that cause diseases like malaria and toxoplasmosis talk to each other, which could help us find new ways to fight them.

Quick facts

Phase['FUNDING_OTHER']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF GEORGIA (nih funded)
Locations1 site (ATHENS, UNITED STATES)
Trial IDNIH-11137015 on ClinicalTrials.gov

What this research studies

Inside every cell, including those of parasites, different tiny compartments need to communicate to function properly. This communication happens at special spots where these compartments touch, allowing them to exchange important materials. For parasites that cause diseases like malaria and toxoplasmosis, this ability to adapt and get nutrients from different environments is key to their survival and spread. By learning how these specific parasites manage their internal communication, we hope to uncover their weaknesses.

Who could benefit from this research

Good fit: This foundational research does not involve direct patient participation but aims to benefit anyone at risk for or suffering from parasitic infections caused by apicomplexans.

Not a fit: Patients not affected by apicomplexan parasites, such as those causing malaria or toxoplasmosis, would not directly benefit from this specific research.

Why it matters

Potential benefit: If successful, this fundamental understanding could lead to the discovery of new targets for medicines to treat or prevent parasitic infections like malaria and toxoplasmosis.

How similar studies have performed: While much is known about cell communication in other organisms, this work explores these processes in apicomplexan parasites, representing a novel area of investigation for these specific disease agents.

Where this research is happening

ATHENS, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.