Latin America-focused breast cancer genetics to improve risk prediction
Official title: Latin America Genomics of Breast Cancer Risk Study (LAGENO-BCR)
Funded at University of California at Davis · NIH-11535294 · Data updated 2026-11-12
A study at UC Davis is building a large, diverse dataset to improve how we predict breast cancer risk for Hispanic/Latina and other Latin American populations.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California at Davis NIH-funded |
| Lab location | 1 site (Davis, United States) |
| Project start | September 1, 2024 |
| Project end | August 31, 2029 |
| Funding year | 2026 |
| Award (this year) | $8,640 |
| NIH project number | 3R01CA286650-03S1 |
| Project ID | NIH-11535294 on NIH RePORTER |
Who could benefit from this research
✓Could help
Women with breast cancer or at risk who self-identify as Latin American or Hispanic/Latina and are part of the study networks.
✕Less likely to help
Women not represented in the study populations or those not contributing samples or data may not directly benefit.
What this research studies
This project brings together thousands of breast cancer patients and healthy women from Latin America and the U.S. to study genetic factors that influence risk. Researchers will analyze germline DNA variants across diverse ancestries and develop risk models that consider ancestry and geography. The goal is to create more accurate, personalized risk scores that reflect genetic diversity beyond European populations. The study relies on collaboration across countries and existing patient data to strengthen breast cancer risk prediction for underrepresented groups.
Why it matters
Potential benefit: If successful, the risk models could help tailor screening and prevention strategies for Latin American populations.
How similar studies have gone: Earlier studies showed improved predictive accuracy when diverse ancestry was included; this project expands that work with a much larger and broader cohort.
Where this research is happening
-
University of California at Davis
Davis, United States Active
Researchers
- Principal investigator: Fejerman, Laura — University of California at Davis
- Study coordinator: Fejerman, Laura
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.