Latin America-focused breast cancer genetic risk and prediction study
Official title: Latin America Genomics of Breast Cancer Risk Study (LAGENO-BCR)
Funded at University of California at Davis · NIH-11535295 · Data updated 2026-11-12
A US university-led study will analyze genetic risk factors for breast cancer in Hispanic/Latina and Latin American women to improve risk prediction models.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California at Davis NIH-funded |
| Lab location | 1 site (Davis, United States) |
| Project start | September 1, 2024 |
| Project end | August 31, 2029 |
| Funding year | 2026 |
| Award (this year) | $46,801 |
| NIH project number | 3R01CA286650-03S2 |
| Project ID | NIH-11535295 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates are women with diverse Latin American or Hispanic/Latina ancestry who are willing to contribute genetic and health information for risk modeling.
✕Less likely to help
Individuals not matching the Latin American/Hispanic/Latina ancestry criteria or not participating in genetic research may not directly benefit.
What this research studies
This project pulls together genetic data from thousands of Latin American and U.S. women to understand how ancestry and geography influence breast cancer risk. Researchers will use genome-wide data to refine risk scores and create models that are more accurate for diverse populations. The aim is to improve early awareness and personalized risk assessment for women who may be at higher risk due to their genetic background. The study involves international collaboration and large-scale genetic analyses to enhance breast cancer prevention efforts.
Why it matters
Potential benefit: If successful, it could lead to more accurate, ancestry-aware breast cancer risk predictions for diverse women, aiding personalized screening decisions.
How similar studies have gone: Prior similar studies have shown that including diverse ancestries improves the accuracy of genetic risk scores, though this project expands the scope substantially.
Where this research is happening
-
University of California at Davis
Davis, United States Active
Researchers
- Principal investigator: Fejerman, Laura — University of California at Davis
- Study coordinator: Fejerman, Laura
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.