NIH-funded research R01 grant

Latin America Breast Cancer Genetics and Risk Modeling

Official title: Latin America Genomics of Breast Cancer Risk Study (LAGENO-BCR)

Funded at University of California at Davis · NIH-11535298 · Data updated 2026-11-12

A large study of diverse Latin American women aims to improve how we predict breast cancer risk using genetic information.

More Breast Cancer research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of California at Davis
NIH-funded
Lab location1 site (Davis, United States)
Project startSeptember 1, 2024
Project endAugust 31, 2029
Funding year2026
Award (this year)$6,480
NIH project number3R01CA286650-03S5
Project IDNIH-11535298 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates are women at risk for breast cancer or with a family history who identify as Latin American or Hispanic/Latina and who have or may contribute genetic data.

Less likely to help

Individuals without or outside the target ancestry group or with no plan to participate in genetic-related data collection may not benefit.

What this research studies

This project brings together data from thousands of women across Latin America and the U.S. diaspora to understand how ancestry and geography affect breast cancer risk. Researchers will combine existing studies to build more accurate risk scores that reflect ancestry diversity. The study will use germline genetic data and existing risk factors to create predictive models that can guide personalized screening for women who may be at higher risk.

Why it matters

Potential benefit: If successful, this work could lead to more accurate, personalized breast cancer risk assessments for diverse populations.

How similar studies have gone: Previous diverse-ancestry GWAS have improved risk prediction, and this larger, multi-country effort aims to enhance accuracy further.

Where this research is happening

  • University of California at Davis
    Davis, United States
    Active

Researchers

  • Principal investigator: Fejerman, Laura — University of California at Davis
  • Study coordinator: Fejerman, Laura

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.