Language development after exposure to viruses before birth

Long-term language outcomes in children with prenatal virus exposure

NIH-funded research Vanderbilt University Medical Center · NIH-11302704

This project looks at how being exposed to viruses in the womb affects language and communication in children born during the Zika outbreak.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionVanderbilt University Medical Center NIH-funded
Lab location1 site (Nashville, United States)
Project IDNIH-11302704 on NIH RePORTER

What this research studies

If your child was born during the 2015–2017 Zika outbreak in Brazil, researchers are following children with and without documented prenatal exposure to compare language and communication over time. They use detailed speech and language tests, behavioral observations, and physiological measures such as auditory testing to find subtle problems that might appear later in childhood even if the newborn exam was normal. The team aims to identify early signs that predict later language differences so families and clinicians can offer support sooner. Participation may involve clinic visits, hearing checks, recordings, and questionnaires about your child's communication.

Who could benefit from this research

Good fit: Children from the Brazilian cohort born during the Zika pandemic with known prenatal exposure status, especially preschool and early school-age children.

Not a fit: Children whose language issues are explained by clear hearing loss at birth or major nonverbal intellectual disability may not gain direct benefit from the study's language-specific findings.

Why it matters

Potential benefit: Could help detect hidden language problems earlier so children can get speech and educational support sooner.

How similar studies have performed: Previous work by this group and others has shown subtle communication delays in Zika-exposed infants and preschoolers, so this builds on emerging evidence rather than being entirely novel.

Where this research is happening

Nashville, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.