NIH-funded research R01 grant

Language and thinking after childhood stroke

Official title: Language and cognition after childhood stroke

Funded at Georgetown University · NIH-11446736 · Data updated 2026-11-12

This project studies how children and teens adapt language after a stroke and what long-term language abilities look like.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionGeorgetown University
NIH-funded
Lab location1 site (Washington, United States)
Project startJuly 1, 2026
Project endJune 30, 2031
Funding year2026
Award (this year)$695,903
NIH project number1R01DC023222-01A1
Project IDNIH-11446736 on NIH RePORTER

Who could benefit from this research

Could help

Adolescents and young adults who had a left-hemisphere stroke during childhood (ages 2–13) and healthy siblings as controls.

Less likely to help

Healthy individuals without a history of childhood stroke may not experience direct benefits from this study.

What this research studies

Researchers at Georgetown University will follow adolescents and young adults who had strokes in childhood to understand how language develops when the brain reorganizes after injury. They will recruit 30 participants with left-side arterial ischemic stroke, 30 with left-side hemorrhagic stroke, and 30 healthy siblings as controls, then test language skills and brain activity. The goal is to map which brain areas support language over the long term and how this changes from childhood into young adulthood. The study builds on earlier findings showing that the right side can take over language tasks after left-hemisphere injury.

Why it matters

Potential benefit: Understanding how the brain compensates for early strokes could guide tailored therapies to support language in affected youths.

How similar studies have gone: Previous work has shown language reorganization after perinatal stroke, suggesting this approach could reveal long-term language outcomes in childhood-stroke survivors.

Where this research is happening

  • Georgetown University
    Washington, United States
    Active

Researchers

  • Principal investigator: Newport, Elissa L — Georgetown University
  • Study coordinator: Newport, Elissa L

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.