Labor Migration, Violence Exposure, and Dementia Risk in Nepal—A Population Study
Official title: Labor Migration, Exposure to Violence and Dementia Risk: A Population Study in Nepal
Funded at Georgetown University · NIH-11377364 · Data updated 2026-11-12
This project studies how social and economic experiences like moving away for work and long-term exposure to conflict may influence dementia risk in adults.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Georgetown University NIH-funded |
| Lab location | 1 site (Washington, United States) |
| Project start | September 30, 2022 |
| Project end | May 31, 2027 |
| Funding year | 2026 |
| Award (this year) | $778,621 |
| NIH project number | 5R01AG074079-05 |
| Project ID | NIH-11377364 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults in Nepal who have experienced labor migration or prolonged exposure to conflict/violence, and who are middle-aged or older.
✕Less likely to help
Individuals without exposure to migration or sustained conflict-related stress may have limited direct benefit.
What this research studies
The study will create a new population-based cohort of middle-aged and older adults in Nepal to explore how life-course factors tied to work migration and exposure to violence affect the risk of Alzheimer’s disease and related dementias. Researchers will examine long-term trajectories of social, economic, and environmental stressors and their links to brain aging, using population data and rigorous analysis. The goal is to better understand how these experiences might influence dementia risk in the U.S. and other settings. The findings could inform prevention strategies that address social determinants of brain health across populations.
Why it matters
Potential benefit: If successful, the work could identify modifiable social factors to reduce ADRD risk in diverse communities.
How similar studies have gone: Previous research links social determinants and stress to dementia risk, but this study adds a cross-cultural perspective with a focus on migration and violence exposure.
Where this research is happening
-
Georgetown University
Washington, United States Active
Researchers
- Principal investigator: Mendes de Leon, Carlos F. — Georgetown University
- Study coordinator: Mendes de Leon, Carlos F.
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.