KwaZulu-Natal HIV and TB clinical trials unit

KwaZulu-Natal Clinical Trials Unit

NIH-funded research Centre/aids Programme/res/south Africa · NIH-11229783

This program runs clinical trials in KwaZulu-Natal to test new HIV prevention tools, vaccines, and treatments for people at risk of or living with HIV and tuberculosis.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionCentre/aids Programme/res/south Africa NIH-funded
Lab location1 site (Durban, SOUTH AFRICA)
Project IDNIH-11229783 on NIH RePORTER

What this research studies

This unit brings together several established research clinics in Durban to run multiple clinical trials focused on HIV and tuberculosis. The combined sites have enrolled thousands of participants and maintain high retention while working with experienced investigators and research staff. Trials include prevention technologies such as vaccines and antibodies as well as treatment and co-treatment strategies for HIV and TB. If you visit one of the participating clinics you may be invited to join a specific trial that fits your health situation.

Who could benefit from this research

Good fit: People in and around Durban who are at risk for HIV or tuberculosis, adolescents and adults eligible under specific trial rules, or people living with HIV who meet trial criteria.

Not a fit: People who are not at risk for HIV/TB, live far from the KZN clinical sites, are outside the studied age groups, or who do not meet individual trial inclusion criteria are unlikely to benefit directly.

Why it matters

Potential benefit: If successful, this program could speed access to better HIV prevention and treatment options and help reduce infections and deaths in the region.

How similar studies have performed: Previous trials run by this unit and partner networks have led to major successes such as tenofovir-based PrEP and improved HIV–TB co-treatment strategies, showing this approach can change care.

Where this research is happening

Durban, SOUTH AFRICA

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Acquired Immune Deficiency SyndromeAcquired Immune Deficiency Syndrome VirusAcquired Immunodeficiency SyndromeAcquired Immunodeficiency Syndrome Virus
Last reviewed 2026-06-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.