KwaZulu-Natal center for HIV and tuberculosis clinical trials

KwaZulu-Natal Clinical Trials Unit

NIH-funded research Centre/aids Programme/res/south Africa · NIH-11397677

Runs clinical trials testing new HIV prevention and treatment approaches for people in KwaZulu-Natal, including adolescents and adults.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionCentre/aids Programme/res/south Africa NIH-funded
Lab location1 site (Durban, SOUTH AFRICA)
Project IDNIH-11397677 on NIH RePORTER

What this research studies

You would take part at clinics run by experienced teams from CAPRISA and the South African Medical Research Council in Durban, which run many HIV and TB trials. The unit combines eight clinical research sites with shared leadership, coordination, and support cores to manage studies and keep high follow-up rates. They test prevention tools (for example the CAPRISA 256 antibody), PrEP strategies, and treatment approaches for people at risk of or living with HIV and tuberculosis. The teams aim to enroll and retain participants from priority populations so new tools can reach the communities hardest hit by HIV/TB.

Who could benefit from this research

Good fit: People living in or near KwaZulu-Natal who are adolescents or adults at risk for HIV or with HIV/TB and willing to join clinical research visits and follow-up would be the best match.

Not a fit: People who live far from the Durban sites, who do not meet a specific trial's eligibility rules, or who need immediate guaranteed treatment may not directly benefit from participation.

Why it matters

Potential benefit: Could speed access to new HIV prevention tools and better treatment strategies for people at high risk or living with HIV/TB in the region.

How similar studies have performed: Teams from these sites have contributed to proven advances such as tenofovir-based PrEP, improved HIV–TB co-treatment strategies, and reduced breastfeeding transmission with nevirapine, so the approach builds on prior successful work.

Where this research is happening

Durban, SOUTH AFRICA

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Acquired Immune Deficiency SyndromeAcquired Immune Deficiency Syndrome VirusAcquired Immunodeficiency SyndromeAcquired Immunodeficiency Syndrome Virus
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.