Kipiyeecipsakiciipe (Coming Home): How traditional cultural practices may help reduce substance misuse

Kipiyeecipsakiciipe "coming home": Establishing clinical cultural neuroscience as a tool for understanding the role of traditional cultural engagement in mitigating substance misuse and disorder

NIH-funded research Laureate Institute for Brain Research · NIH-11090570

This project will look at how traditional cultural engagement affects brain patterns linked to substance misuse among American Indian adults.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionLaureate Institute for Brain Research NIH-funded
Lab location1 site (Tulsa, United States)
Project IDNIH-11090570 on NIH RePORTER

What this research studies

You would join a community-partnered project led with the Shawnee Tribe to define what traditional cultural engagement means in local terms. Participants who are American Indian adults would be invited to share experiences, complete behavioral measures, and undergo noninvasive brain scans using multiple neuroimaging methods. The team will compare brain structure and function markers with levels of cultural engagement and substance use to understand possible protective processes. Results will be interpreted and shared with community partners to guide culturally grounded supports.

Who could benefit from this research

Good fit: Ideal candidates are American Indian adults aged 21 or older who are willing to work with community partners, share their experiences, and attend study visits including MRI scans.

Not a fit: People under 21, non–American Indian individuals, or those unable to undergo MRI (for example due to certain implants or claustrophobia) may not be eligible or benefit from participation.

Why it matters

Potential benefit: If successful, the work could point to culturally based approaches that protect against substance misuse and help shape culturally relevant supports or treatments for American Indian communities.

How similar studies have performed: Prior work shows culturally grounded programs can lower substance use and neuroscience can detect brain changes after behavioral interventions, but combining clinical neuroscience with traditional cultural engagement in American Indian communities is a novel approach.

Where this research is happening

Tulsa, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.