KF Modified Story Memory Technique to improve new learning and memory in mild cognitive impairment

Use of the KF Modified Story Memory Technique to Improve New Learning and Memory in Individuals with Mild Cognitive Impairment

NIH-funded research Kessler Foundation, INC. · NIH-11132826

This project sees if a 10-session KF-mSMT memory-training program helps older adults with mild cognitive impairment learn and remember new information.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionKessler Foundation, INC. NIH-funded
Lab location1 site (East Hanover, UNITED STATES)
Project IDNIH-11132826 on NIH RePORTER

What this research studies

You would take part in a multi-site, double-blind, placebo-controlled trial comparing a manualized 10-session memory training program (KF-mSMT) to a control condition. Sessions focus on a story-based strategy to help encode and recall new information, with trained staff delivering the program according to a manual. The trial will measure memory on objective tests, brain-related outcomes, and everyday functioning, with follow-up to see whether benefits last. The work builds on prior research in other neurologic conditions and pilot data in people with MCI.

Who could benefit from this research

Good fit: Ideal candidates are adults diagnosed with mild cognitive impairment who can attend the program sessions and complete memory testing and follow-up visits.

Not a fit: People with more advanced dementia, severe medical or psychiatric conditions, or those unable to participate in regular visits or follow instructions are unlikely to benefit from this intervention.

Why it matters

Potential benefit: If successful, this program could help people with MCI remember everyday information better and support independence in daily activities.

How similar studies have performed: Related KF-mSMT work has improved learning and memory in conditions like MS and TBI and early pilot data in MCI are promising, but this is a larger controlled trial to confirm effects.

Where this research is happening

East Hanover, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.