Kaposi sarcoma clinical and research hub for people living with HIV

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NIH-funded research Lsu Health Sciences Center · NIH-11415852

This program brings hospitals and researchers in the U.S., Zambia, and Tanzania together to improve diagnosis, care, and research on Kaposi sarcoma for people living with HIV.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionLsu Health Sciences Center NIH-funded
Lab location1 site (New Orleans, United States)
Project IDNIH-11415852 on NIH RePORTER

What this research studies

Partner hospitals in New Orleans, Zambia, and Tanzania will integrate Kaposi sarcoma (KS) diagnosis and care into existing HIV clinic networks, train local clinicians, and coordinate research. The program will collect blood and tissue samples and use immune and metabolomic tests to look for markers tied to KS stage and treatment response. Researchers will map where Kaposi sarcoma herpesvirus (KSHV) hides in body tissues of people with HIV to learn how viral reactivation leads to KS. Clinical tracking, laboratory assays, and shared data across sites will guide future ways to prevent or better treat KS.

Who could benefit from this research

Good fit: Ideal candidates are people living with HIV who have Kaposi sarcoma or are at increased risk for KS and who receive care at the partner hospitals or affiliated HIV clinics in Zambia, Tanzania, or New Orleans.

Not a fit: People without HIV, those with unrelated cancers, or patients who are not served by the partner sites are unlikely to directly benefit from participation.

Why it matters

Potential benefit: If successful, this work could help diagnose KS earlier, guide better treatments, and point to ways to stop the virus from reactivating and causing new KS cases.

How similar studies have performed: Previous collaborations among these groups have improved KS care and biomarker research in the region, while efforts to define and target KSHV tissue reservoirs remain relatively new.

Where this research is happening

New Orleans, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions AIDS associated cancerAIDS related cancerAcquired Immune Deficiency Syndrome VirusAcquired Immunodeficiency Syndrome VirusCancer Center
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.