Joining and staying in a diverse Alzheimer’s memory and white-matter brain health program
Recruitment and Retention Core
['FUNDING_OTHER'] · UNIVERSITY OF CALIFORNIA AT DAVIS · NIH-11320712
This project signs up and keeps a diverse group of people who have small white matter changes on brain scans and memory or thinking concerns so their thinking and brain health can be followed over time.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF CALIFORNIA AT DAVIS (nih funded) |
| Locations | 1 site (DAVIS, UNITED STATES) |
| Trial ID | NIH-11320712 on ClinicalTrials.gov |
What this research studies
You would be invited to join a large, diverse group of 2,250 Black, Hispanic, and White volunteers who have incidental white matter hyperintensities (WMH) on brain imaging and who report cognitive complaints. Participants receive baseline cognitive testing and periodic follow-up visits so researchers can see how thinking changes over time. The team uses community-based approaches and tailored digital outreach tools to recruit people from different backgrounds and help them stay involved. The program is phased in over time and run by the UC Davis Alzheimer’s Disease Research Center, which has a long history of working with minority communities.
Who could benefit from this research
Good fit: Adults who identify as Black, Hispanic, or White who have incidental white matter hyperintensities on brain imaging and have memory or thinking complaints, and who can attend baseline and follow-up visits, are ideal candidates.
Not a fit: People without white matter hyperintensities, without cognitive complaints, or who cannot participate in follow-up visits are unlikely to benefit from this project.
Why it matters
Potential benefit: If successful, this work could improve understanding of how small white matter brain changes relate to memory decline and make it easier for diverse communities to join future Alzheimer's research.
How similar studies have performed: UC Davis has decades of successful minority recruitment and retention in Alzheimer’s research, though combining those community methods with new digital 'e-tools' for precision engagement is a relatively new approach.
Where this research is happening
DAVIS, UNITED STATES
- UNIVERSITY OF CALIFORNIA AT DAVIS — DAVIS, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: JOHNSON, DAVID K — UNIVERSITY OF CALIFORNIA AT DAVIS
- Study coordinator: JOHNSON, DAVID K
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Alzheimer disease dementia, Alzheimer syndrome, Alzheimer's Disease, Alzheimer's disease and related dementia