Johns Hopkins Uganda HIV Prevention and Treatment Trials

The Johns Hopkins University - Uganda Clinical Trials Unit

NIH-funded research Johns Hopkins University · NIH-11458377

Tests new HIV vaccines, prevention approaches, and treatments for adults, pregnant women, and children served by clinics in Uganda.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionJohns Hopkins University NIH-funded
Lab location1 site (Baltimore, United States)
Project IDNIH-11458377 on NIH RePORTER

What this research studies

You would join local clinic sites in Kampala or Rakai where researchers run trials of vaccines, prevention strategies, and new HIV therapies. The unit has long-running sites focused on preventing mother-to-child transmission, pediatric HIV care, and prevention for high-risk women, and is adding adult treatment and vaccine programs to reach more people. Trials are run in partnership with international DAIDS clinical networks and build on decades of experience in Uganda. Participation typically involves medical exams, blood tests, follow-up visits, and sometimes taking study medications or vaccines.

Who could benefit from this research

Good fit: People living with HIV, pregnant or breastfeeding women, high-risk HIV-negative women, and eligible children connected to participating clinics in Kampala or Rakai are the ideal candidates.

Not a fit: People who live outside the study areas, do not meet the age or risk criteria, or have medical conditions that make them ineligible are unlikely to benefit directly from this effort.

Why it matters

Potential benefit: Could lead to safer, more effective HIV vaccines, prevention methods, and treatments that reduce infections and improve care for people in Uganda and beyond.

How similar studies have performed: Previous Johns Hopkins and DAIDS-supported trials have produced important advances in PMTCT and HIV treatment, while vaccine work remains promising but challenging.

Where this research is happening

Baltimore, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Acquired Immune Deficiency Syndrome VirusAcquired Immunodeficiency Syndrome Virus
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.