Job insecurity and alcohol and drug use in U.S. adults

Employment Insecurity and Substance Use in U.S. Adults

['FUNDING_R01'] · UNIVERSITY OF SOUTHERN CALIFORNIA · NIH-11323583

This project looks at how losing a job or being underemployed changes alcohol and drug use among U.S. adults, especially after the COVID-19 pandemic.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF SOUTHERN CALIFORNIA (nih funded)
Locations1 site (Los Angeles, UNITED STATES)
Trial IDNIH-11323583 on ClinicalTrials.gov

What this research studies

From your perspective, researchers will analyze existing U.S. survey data collected over time to track when people move into unemployment or underemployment and whether substance use changes afterward. The work includes both job loss and reduced work hours, and compares different groups by age, race/ethnicity, income, and region to see who is most affected. The team uses more frequent timing than typical national surveys to pinpoint short-term and longer-term effects and to examine how community-level factors may buffer or amplify those effects. Findings are intended to inform policies and targeted supports to reduce substance use linked to job instability.

Who could benefit from this research

Good fit: U.S. adults aged 21 and older who have experienced unemployment or underemployment, particularly since the COVID-19 pandemic.

Not a fit: People younger than 21, those living outside the United States, or individuals whose substance use is unrelated to employment stress may not directly benefit from this work.

Why it matters

Potential benefit: If successful, the findings could help target job, financial, and treatment supports to prevent increases in alcohol and drug use after job loss.

How similar studies have performed: Prior cross-sectional studies show links between employment insecurity and substance use, but prospective and causal evidence is mixed, so this longitudinal secondary analysis is relatively novel in its focus on timing and subgroup differences.

Where this research is happening

Los Angeles, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.