Investigating withdrawal symptoms from ultra-processed foods in humans

A Biopsychobehavioral Investigation of Withdrawal from Ultra-Processed Food in Humans

NIH-funded research University of Michigan at Ann Arbor · NIH-10868614

This study is looking at how cutting back on ultra-processed foods might cause some people to feel withdrawal symptoms, similar to what happens when someone stops using certain substances, and it's for anyone interested in understanding the challenges of eating healthier.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Michigan at Ann Arbor NIH-funded
Lab location1 site (Ann Arbor, United States)
Project IDNIH-10868614 on NIH RePORTER

What this research studies

This research explores how reducing ultra-processed food intake may lead to withdrawal symptoms similar to those seen in substance use disorders. It aims to understand the physical, cognitive, and emotional challenges that individuals may face when they stop consuming these foods. By examining the motivational responses to food cues during abstinence, the study seeks to identify potential barriers to maintaining a healthier diet. Participants will be monitored for changes in their cravings and withdrawal symptoms as they reduce their intake of ultra-processed foods.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals who consume a high amount of ultra-processed foods and are interested in reducing their intake.

Not a fit: Patients who do not consume ultra-processed foods or have no interest in dietary changes may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could help develop strategies to support individuals in making healthier dietary choices and overcoming cravings associated with ultra-processed foods.

How similar studies have performed: While there is substantial evidence from animal models regarding withdrawal from ultra-processed foods, this research is among the first to investigate these effects in humans.

Where this research is happening

Ann Arbor, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.